5'-O-DMT-2'-O-tert-Butyldimethylsilyl-uridine 3'-CE phosphoramidite
5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS: 118362-03-1
Molecular Formula: C45H61N4O9PSi
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-uridine 3'-CE phosphoramidite - Names and Identifiers
| Name | 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite |
| Synonyms | 2'-TBDMS-U CEP rU Phosphoramidite 2'-TBDMS-rU Phosphoramidite 2'-TBDMS-rU Phosphoramidite 5'-O-DMT-2'-TBDMS-rU-3'-CEDPA 5'-DMT-2'-TBDMS-rU Phosphoramidite DMT-2'O-TBDMS-rU Amidite 4g, 12Pack 5'-DMT-2'-O-TBDMS-Uridine Phosphoramidite 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-Uridine 3'-CE phosphoramidite 3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-4-[(TERT-BUTYLDIMETHYLSILYL)OXY]-5-(2,4-DIOXO- 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite |
| CAS | 118362-03-1 |
| EINECS | 200-100-5 |
| InChIKey | SKNLXHRBXYGJOC-ZMHKPELYSA-N |
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-uridine 3'-CE phosphoramidite - Physico-chemical Properties
| Molecular Formula | C45H61N4O9PSi |
| Molar Mass | 861.05 |
| Appearance | powder |
| Color | white to off-white |
| pKa | 9.39±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| MDL | MFCD00080343 |
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-uridine 3'-CE phosphoramidite - Risk and Safety
| WGK Germany | 3 |
| HS Code | 29349990 |
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-uridine 3'-CE phosphoramidite - Introduction
5 '-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl) dimethylsilyl] uridine -3 '-(2-cyanoethyl-N, N-Diisopropyl) phosphoramidite is a compound with the following properties and uses:
Nature:
-Appearance: White solid
-Molecular formula: C36H55N5O5P
-Molecular weight: 679.82g/mol
-Melting point: about 180-185°C
Use:
- 5 '-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl) dimethylsilyl] uridine -3 '-(2-cyanoethyl-N, N-diisopropyl) phosphoramidite is a compound capable of modifying the structure of nucleic acids. In biochemical and molecular biological studies, the compounds can be used to synthesize improved nucleic acid molecules to enhance their stability, selectivity and function. It is often used to modify the nucleic acid chain of DNA or RNA, and is used to explore gene expression, protein synthesis, drug screening and other fields.
Preparation Method:
- 5 '-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl) dimethylsilyl] uridine -3 '-(2-cyanoethyl-N,N-diisopropyl) phosphoramidite The preparation method is more complicated, and generally requires organic synthesis technology and related reagents. Detailed preparation methods can be found in the relevant literature.
Safety Information:
- 5 '-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl) dimethylsilyl] uridine -3 '-(2-cyanoethyl-N,N-Diisopropyl) phosphoramidite is relatively safe under correct use and storage conditions. But as a chemical reagent, still need to pay attention to the following safety matters:
-Avoid contact with skin and eyes. If you do, rinse immediately with plenty of water.
-Avoid inhaling the dust or vapor of the solution, and operate in a well-ventilated place.
-Before use, learn more about the toxicity and dangers of the compound, and take appropriate safety measures, such as wearing protective gloves, glasses and laboratory coats.
-When disposing of waste, please comply with relevant regulations and safety requirements to ensure safe disposal.
Nature:
-Appearance: White solid
-Molecular formula: C36H55N5O5P
-Molecular weight: 679.82g/mol
-Melting point: about 180-185°C
Use:
- 5 '-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl) dimethylsilyl] uridine -3 '-(2-cyanoethyl-N, N-diisopropyl) phosphoramidite is a compound capable of modifying the structure of nucleic acids. In biochemical and molecular biological studies, the compounds can be used to synthesize improved nucleic acid molecules to enhance their stability, selectivity and function. It is often used to modify the nucleic acid chain of DNA or RNA, and is used to explore gene expression, protein synthesis, drug screening and other fields.
Preparation Method:
- 5 '-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl) dimethylsilyl] uridine -3 '-(2-cyanoethyl-N,N-diisopropyl) phosphoramidite The preparation method is more complicated, and generally requires organic synthesis technology and related reagents. Detailed preparation methods can be found in the relevant literature.
Safety Information:
- 5 '-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl) dimethylsilyl] uridine -3 '-(2-cyanoethyl-N,N-Diisopropyl) phosphoramidite is relatively safe under correct use and storage conditions. But as a chemical reagent, still need to pay attention to the following safety matters:
-Avoid contact with skin and eyes. If you do, rinse immediately with plenty of water.
-Avoid inhaling the dust or vapor of the solution, and operate in a well-ventilated place.
-Before use, learn more about the toxicity and dangers of the compound, and take appropriate safety measures, such as wearing protective gloves, glasses and laboratory coats.
-When disposing of waste, please comply with relevant regulations and safety requirements to ensure safe disposal.
Last Update：2024-04-09 19:05:45
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View History
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-uridine 3'-CE phosphoramidite
5-Azaspiro[2.4]heptane-6-carboxylic acid, (6S)-
4H-1-Benzopyran-4-one, 6-[(6-O-acetyl-β-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-
3-甲基苯并[D]异恶唑
[N,N'-bis[2-(hexadecyloxy)-2-oxoethyl]-N-[2-[[2-(hexadecyloxy)-2-oxoethyl]dimethylammonio]ethyl]-N,N',N'-trimethyl]ethylenediammonium trichloride
5-Azaspiro[2.4]heptane-6-carboxylic acid, (6S)-
4H-1-Benzopyran-4-one, 6-[(6-O-acetyl-β-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-
3-甲基苯并[D]异恶唑
[N,N'-bis[2-(hexadecyloxy)-2-oxoethyl]-N-[2-[[2-(hexadecyloxy)-2-oxoethyl]dimethylammonio]ethyl]-N,N',N'-trimethyl]ethylenediammonium trichloride